Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.P42P

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000600.5
p.P42P
c.126A>G
Surrounding Variants
1 paper
NM_000600.5
p.P42P
c.126A>T
1 paper
NM_000600.5
p.H43N
c.127C>A
2 papers
NM_000600.5
p.H43Y
c.127C>T
1 paper
NM_000600.5
p.P42A
c.124C>G
1 paper
NM_000600.5
p.P42S
c.124C>T
1 paper
NM_000600.5
p.H43Q
c.129C>G
1 paper
NM_000600.5
p.H43H
c.129C>T
1 paper
NM_000600.5
p.R44*
c.130A>T
1 paper
NM_000600.5
p.A41fs
c.121_122fs
1 paper
NM_000600.5
p.R44R
c.132A>G
2 papers
NM_000600.5
p.Q45K
c.133C>A
1 paper
NM_000600.5
p.A40V
c.119C>T
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