Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.P46insFs

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.P46insFs
c.137_138insT
Surrounding Variants
5 papers
NM_000600.5
p.P46R
c.137C>G
10 papers
NM_000600.5
p.P46L
c.137C>T
1 paper
NM_000600.5
p.P46P
c.138A>G
1 paper
NM_000600.5
p.P46A
c.136C>G
1 paper
NM_000600.5
p.L47F
c.139C>T
1 paper
NM_000600.5
p.Q45Q
c.135G>A
1 paper
NM_000600.5
p.Q45H
c.135G>C
2 papers
NM_000600.5
p.Q45K
c.133C>A
1 paper
NM_000600.5
p.L47L
c.141C>A
1 paper
NM_000600.5
p.Q45*
c.133C>T
1 paper
NM_000600.5
p.R44R
c.132A>G
1 paper
NM_000600.5
p.T48N
c.143C>A
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