Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.D54V

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.D54V
c.161A>T
Surrounding Variants
4 papers
NM_000600.5
p.D54G
c.161A>G
2 papers
NM_000600.5
p.K55E
c.163A>G
1 paper
NM_000600.5
p.K55_I60del0
c.165_179del15
1 paper
NM_000600.5
p.I53_D54insT
c.157_161ins3
1 paper
NM_000600.5
p.I53F
c.157A>T
1 paper
NM_000600.5
p.Q56_I60del0
c.166_180del15
1 paper
NM_000600.5
p.I53delFs
c.158delT
5 papers
NM_000600.5
p.R52Q
c.155G>A
2 papers
NM_000600.5
p.R52L
c.155G>T
1 paper
NM_000600.5
p.Q56H
c.168A>T
2 papers
NM_000600.5
p.R52*
c.154C>T
1 paper
NM_000600.5
p.E51V
c.152A>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."