Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.E87K

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.E87K
c.259G>A
Surrounding Variants
1 paper
NM_000600.5
p.E87Q
c.259G>C
4 papers
NM_000600.5
p.N88S
c.263A>G
1 paper
NM_000600.5
p.N89Y
c.265A>T
12 papers
NM_000600.5
p.A84A
c.252A>G
2 papers
NM_000600.5
p.A84A
c.252A>T
2 papers
NM_000600.5
p.N89K
c.267C>A
2 papers
NM_000600.5
p.N89K
c.267C>G
2 papers
NM_000600.5
p.N89N
c.267C>T
1 paper
NM_000600.5
p.A84V
c.251C>T
2 papers
NM_000600.5
p.L90L
c.268C>T
3 papers
NM_000600.5
p.A84T
c.250G>A
1 paper
NM_000600.5
p.E83E
c.249G>A
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