Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.K98N

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.K98N
c.294A>T
Surrounding Variants
1 paper
NM_000600.5
p.K98_S104del0
c.294_311del18
2 papers
NM_000600.5
p.D99Y
c.295G>T
1 paper
NM_000600.5
p.E97G
c.290A>G
6 papers
NM_000600.5
p.G100E
c.299G>A
3 papers
NM_000600.5
p.A96A
c.288T>A
1 paper
NM_000600.5
p.A96A
c.288T>G
1 paper
NM_000600.5
p.C101S
c.302G>C
1 paper
NM_000600.5
p.F102_E108insFs
c.304_323dup20
1 paper
NM_000600.5
p.M95L
c.283A>T
1 paper
NM_000600.5
p.M95delFs
c.284_285delTG
1 paper
NM_000600.5
p.K94K
c.282G>A
1 paper
NM_000600.5
p.Q103P
c.308A>C
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