Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.E121D

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.E121D
c.363G>C
Surrounding Variants
1 paper
NM_000600.5
p.E121D
c.363G>T
2 papers
NM_000600.5
p.E123K
c.367G>A
2 papers
NM_000600.5
p.L120S
c.359T>C
1 paper
NM_000600.5
p.E123A
c.368A>C
1 paper
NM_000600.5
p.E123G
c.368A>G
1 paper
NM_000600.5
p.V124delFs
c.370delG
1 paper
NM_000600.5
p.L119L
c.357T>G
1 paper
NM_000600.5
p.L119insFs
c.356_357ins4
1 paper
NM_000600.5
p.L119V
c.355C>G
1 paper
NM_000600.5
p.L119F
c.355C>T
1 paper
NM_000600.5
p.V124V
c.372A>G
1 paper
NM_000600.5
p.G118G
c.354T>A
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