Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.A142A

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.A142A
c.426T>C
Surrounding Variants
1 paper
NM_000600.5
p.A142D
c.425C>A
1 paper
NM_000600.5
p.A142T
c.424G>A
1 paper
NM_000600.5
p.A142fs
c.424_425fs
2 papers
NM_000600.5
p.V143A
c.428T>C
1 paper
NM_000600.5
p.Q144P
c.431A>C
1 paper
NM_000600.5
p.R141G
c.421A>G
1 paper
NM_000600.5
p.Q144L
c.431A>T
10 papers
NM_000600.5
p.A140A
c.420C>G
1 paper
NM_000600.5
p.A140D
c.419C>A
1 paper
NM_000600.5
p.A140_A142delFs
c.420_426del7
1 paper
NM_000600.5
p.A140T
c.418G>A
1 paper
NM_000600.5
p.A140P
c.418G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."