Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.F153insFs

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.F153insFs
c.457_458insG
Surrounding Variants
1 paper
NM_000600.5
p.F153L
c.457T>C
1 paper
NM_000600.5
p.F153C
c.458T>G
1 paper
NM_000600.5
p.Q152L
c.455A>T
1 paper
NM_000600.5
p.F153L
c.459C>A
1 paper
NM_000600.5
p.F153L
c.459C>G
6 papers
NM_000600.5
p.L154L
c.460C>T
1 paper
NM_000600.5
p.Q152*
c.454C>T
1 paper
NM_000600.5
p.L154L
c.462G>T
2 papers
NM_000600.5
p.I151V
c.451A>G
1 paper
NM_000600.5
p.Q155K
c.463C>A
1 paper
NM_000600.5
p.Q155H
c.465G>C
1 paper
NM_000600.5
p.Q155H
c.465G>T
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