Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.K159N

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.K159N
c.477G>T
Surrounding Variants
1 paper
NM_000600.5
p.K159N
c.477G>C
3 papers
NM_000600.5
p.K159*
c.475A>T
1 paper
NM_000600.5
p.L161delFs
c.481_482delCT
1 paper
NM_000600.5
p.L161delFs
c.481delC
1 paper
NM_000600.5
p.A158_L161del0
c.472_483del12
11 papers
NM_000600.5
p.D162V
c.485A>T
13 papers
NM_000600.5
p.D162E
c.486T>A
13 papers
NM_000600.5
p.D162E
c.486T>G
1 paper
NM_000600.5
p.A163P
c.487G>C
1 paper
NM_000600.5
p.I164K
c.491T>A
1 paper
NM_000600.5
p.T165_L179del15
c.493_536del45
1 paper
NM_000600.5
p.T166_Q180del15
c.496_539del45
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."