Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.I194T

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.I194T
c.581T>C
Surrounding Variants
1 paper
NM_000600.5
p.R196_L206del11
c.586_617del33
1 paper
NM_000600.5
p.L195P
c.584T>C
1 paper
NM_000600.5
p.R196_S204del0
c.586_612del27
2 papers
NM_000600.5
p.R196S
c.586C>A
1 paper
NM_000600.5
p.R196G
c.586C>G
2 papers
NM_000600.5
p.R196C
c.586C>T
1 paper
NM_000600.5
p.R196H
c.587G>A
1 paper
NM_000600.5
p.R196R
c.588C>T
202 papers
NM_000600.5
p.T191S
c.572C>G
3 papers
NM_000600.5
p.T191I
c.572C>T
1 paper
NM_000600.5
p.H192_I194del3
c.574_581del9
1 paper
NM_000600.5
p.T190T
c.570A>G
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