Varaico: Literature-Extracted Genetic Variants

Gene:IL6R
Variant:p.L2L

IL6R

691 papers

RefSeq Summary

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in th...

Pfam Domains

igaa 34–99UCSCImmunoglobulin domain
IL6Ra-bindaa 118–213UCSCInterleukin-6 receptor alpha chain, binding

Gene Aliases

HGNC Name

interleukin 6 receptor

HGNC Alias Symbols

CD126; IL-6R; IL-1Ra; IL6RA; gp80

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000565.4
p.L2L
c.6G>C
Surrounding Variants
2 papers
NM_000565.4
p.L2L
c.6G>A
1 paper
NM_000565.4
p.L2insFs
c.4_5insT
1 paper
NM_000565.4
p.L2L
c.4C>T
1 paper
NM_000565.4
p.V4delFs
c.10_11delGT
1 paper
NM_000565.4
p.M1I
c.3G>C
1 paper
NM_000565.4
p.M1K
c.2T>A
1 paper
NM_000565.4
p.V4A
c.11T>C
1 paper
NM_000565.4
p.G5S
c.13G>A
1 paper
NM_000565.4
p.G5R
c.13G>C
1 paper
NM_000565.4
p.C6insFs
c.17_18insT
1 paper
NM_000565.4
p.L9L
c.25C>T
1 paper
NM_000565.4
p.L9L
c.27G>A
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