Varaico: Literature-Extracted Genetic Variants

Gene:IL6R
Variant:p.P22S

IL6R

691 papers

RefSeq Summary

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in th...

Pfam Domains

igaa 34–99UCSCImmunoglobulin domain
IL6Ra-bindaa 118–213UCSCInterleukin-6 receptor alpha chain, binding

Gene Aliases

HGNC Name

interleukin 6 receptor

HGNC Alias Symbols

CD126; IL-6R; IL-1Ra; IL6RA; gp80

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000565.4
p.P22S
c.64C>T
Surrounding Variants
1 paper
NM_000565.4
p.A21A
c.63C>G
1 paper
NM_000565.4
p.L20L
c.60G>A
1 paper
NM_000565.4
p.R24G
c.70C>G
2 papers
NM_000565.4
p.C25S
c.74G>C
1 paper
NM_000565.4
p.P26S
c.76C>T
1 paper
NM_000565.4
p.P16L
c.47C>T
1 paper
NM_000565.4
p.A11A
c.33C>A
1 paper
NM_000565.4
p.A11A
c.33C>G
1 paper
NM_000565.4
p.A11T
c.31G>A
1 paper
NM_000565.4
p.A10D
c.29C>A
1 paper
NM_000565.4
p.L9L
c.27G>A
1 paper
NM_000565.4
p.L9L
c.25C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."