Varaico: Literature-Extracted Genetic Variants

Gene:IL6R
Variant:p.C165S

IL6R

691 papers

RefSeq Summary

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in th...

Pfam Domains

igaa 34–99UCSCImmunoglobulin domain
IL6Ra-bindaa 118–213UCSCInterleukin-6 receptor alpha chain, binding

Gene Aliases

HGNC Name

interleukin 6 receptor

HGNC Alias Symbols

CD126; IL-6R; IL-1Ra; IL6RA; gp80

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000565.4
p.C165S
c.494G>C
Surrounding Variants
1 paper
NM_000565.4
p.C165S
c.493T>A
1 paper
NM_000565.4
p.Y167S
c.500A>C
1 paper
NM_000565.4
p.S168A
c.502T>G
1 paper
NM_000565.4
p.Q162P
c.485A>C
1 paper
NM_000565.4
p.Q162L
c.485A>T
1 paper
NM_000565.4
p.D160E
c.480C>A
1 paper
NM_000565.4
p.D160E
c.480C>G
1 paper
NM_000565.4
p.D160G
c.479A>G
7 papers
NM_000565.4
p.S171P
c.511T>C
1 paper
NM_000565.4
p.Q172L
c.515A>T
1 paper
NM_000565.4
p.Q172H
c.516G>T
1 paper
NM_000565.4
p.K173Q
c.517A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."