Varaico: Literature-Extracted Genetic Variants

Gene:IL6R
Variant:p.H275Q

IL6R

691 papers

RefSeq Summary

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in th...

Pfam Domains

igaa 34–99UCSCImmunoglobulin domain
IL6Ra-bindaa 118–213UCSCInterleukin-6 receptor alpha chain, binding

Gene Aliases

HGNC Name

interleukin 6 receptor

HGNC Alias Symbols

CD126; IL-6R; IL-1Ra; IL6RA; gp80

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000565.4
p.H275Q
c.825T>G
Surrounding Variants
1 paper
NM_000565.4
p.H275Q
c.825T>A
1 paper
NM_000565.4
p.C277R
c.829T>C
1 paper
NM_000565.4
p.C277Y
c.830G>A
1 paper
NM_000565.4
p.C277F
c.830G>T
3 papers
NM_000565.4
p.L273L
c.819C>T
1 paper
NM_000565.4
p.I279del1
c.835_836delATC
1 paper
NM_000565.4
p.V278G
c.833T>G
1 paper
NM_000565.4
p.I279delFs
c.836_837delTC
1 paper
NM_000565.4
p.D272Y
c.814G>T
2 papers
NM_000565.4
p.I279N
c.836T>A
1 paper
NM_000565.4
p.H280N
c.838C>A
1 paper
NM_000565.4
p.H280P
c.839A>C
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