Varaico: Literature-Extracted Genetic Variants

Gene:IL7
Variant:p.N58S

IL7

162 papers

RefSeq Summary

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth...

Pfam Domains

IL7aa 26–79UCSCInterleukin 7
IL7aa 74–115UCSCInterleukin 7

Gene Aliases

HGNC Name

interleukin 7

HGNC Alias Symbol

IL-7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000880.4
p.N58S
c.173A>G
Surrounding Variants
2 papers
NM_000880.4
p.I55M
c.165T>G
1 paper
NM_000880.4
p.N62D
c.184A>G
1 paper
NM_000880.4
p.E54V
c.161A>T
1 paper
NM_000880.4
p.E63K
c.187G>A
1 paper
NM_000880.4
p.F64S
c.191T>C
1 paper
NM_000880.4
p.M52V
c.154A>G
1 paper
NM_000880.4
p.D50_S51insFs
c.150_151ins4
1 paper
NM_000880.4
p.F66S
c.197T>C
1 paper
NM_000880.4
p.K68Q
c.202A>C
4 papers
NM_000880.4
p.R69*
c.205A>T
1 paper
NM_000880.4
p.D73N
c.217G>A
1 paper
NM_000880.4
p.K76delFs
c.227delT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."