Varaico: Literature-Extracted Genetic Variants

IL7R

720 papers

RefSeq Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by ...

Pfam Domains

FN3_7aa 32–127UCSCFibronectin type III domain

fn3aa 130–224UCSCFibronectin type III domain

Gene Aliases

HGNC Name

interleukin 7 receptor

HGNC Alias Symbols

CD127; IL7RA; lnc-IL7R; IL-7Ralpha; IL7Ralpha; sIL-7R; CDw127

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002185.5

p.I121V

c.361A>G

Surrounding Variants

4 papers

NM_002185.5

p.I121fs

c.361_362fs

2 papers

NM_002185.5

p.I121fs

c.361_362fs

2 papers

NM_002185.5

p.K120N

c.360A>C

2 papers

NM_002185.5

p.K120N

c.360A>T

1 paper

NM_002185.5

p.K120Q

c.358A>C

2 papers

NM_002185.5

p.D122H

c.364G>C

1 paper

NM_002185.5

p.D122D

c.366C>T

2 papers

NM_002185.5

p.C118*

c.354C>A

11 papers

NM_002185.5

p.I121insFs

c.361dupA

2 papers

NM_002185.5

p.I121delFs

c.361delA

21 papers

NM_002185.5

p.C118Y

c.353G>A

1 paper

NM_002185.5

p.C118F

c.353G>T