Varaico: Literature-Extracted Genetic Variants

IL7R

720 papers

RefSeq Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by ...

Pfam Domains

FN3_7aa 32–127UCSCFibronectin type III domain

fn3aa 130–224UCSCFibronectin type III domain

Gene Aliases

HGNC Name

interleukin 7 receptor

HGNC Alias Symbols

CD127; IL7RA; lnc-IL7R; IL-7Ralpha; IL7Ralpha; sIL-7R; CDw127

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002185.5

p.S136T

c.407G>C

Surrounding Variants

1 paper

NM_002185.5

p.S136N

c.407G>A

2 papers

NM_002185.5

p.L135R

c.404T>G

1 paper

NM_002185.5

p.V138_Y139delFs

c.412_415del4

43 papers

NM_002185.5

p.V138I

c.412G>A

1 paper

NM_002185.5

p.V138fs

c.412_413fs

1 paper

NM_002185.5

p.D134Y

c.400G>T

1 paper

NM_002185.5

p.F133L

c.399T>A

1 paper

NM_002185.5

p.Y139Y

c.417T>C

2 papers

NM_002185.5

p.R140W

c.418C>T

1 paper

NM_002185.5

p.P132H

c.395C>A

6 papers

NM_002185.5

p.R140Q

c.419G>A

1 paper

NM_002185.5

p.R140P

c.419G>C