Varaico: Literature-Extracted Genetic Variants

IL7R

720 papers

RefSeq Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by ...

Pfam Domains

FN3_7aa 32–127UCSCFibronectin type III domain

fn3aa 130–224UCSCFibronectin type III domain

Gene Aliases

HGNC Name

interleukin 7 receptor

HGNC Alias Symbols

CD127; IL7RA; lnc-IL7R; IL-7Ralpha; IL7Ralpha; sIL-7R; CDw127

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002185.5

p.L190F

c.568C>T

Surrounding Variants

1 paper

NM_002185.5

p.L191M

c.571C>A

1 paper

NM_002185.5

p.Q192fs

c.574_575fs

2 papers

NM_002185.5

p.L188V

c.562C>G

1 paper

NM_002185.5

p.Q192_K194delFs

c.576_582del7

1 paper

NM_002185.5

p.K187K

c.561G>A

4 papers

NM_002185.5

p.L188delFs

c.562delC

1 paper

NM_002185.5

p.Q192H

c.576G>C

1 paper

NM_002185.5

p.Q192H

c.576G>T

1 paper

NM_002185.5

p.T186I

c.557C>T

1 paper

NM_002185.5

p.K194insFs

c.580_581insT

1 paper

NM_002185.5

p.K194Fs

c.581_582delinsTFs

1 paper

NM_002185.5

p.S185I

c.554G>T