Varaico: Literature-Extracted Genetic Variants

IL7R

720 papers

RefSeq Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by ...

Pfam Domains

FN3_7aa 32–127UCSCFibronectin type III domain

fn3aa 130–224UCSCFibronectin type III domain

Gene Aliases

HGNC Name

interleukin 7 receptor

HGNC Alias Symbols

CD127; IL7RA; lnc-IL7R; IL-7Ralpha; IL7Ralpha; sIL-7R; CDw127

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002185.5

p.P418Q

c.1253C>A

Surrounding Variants

1 paper

NM_002185.5

p.P418A

c.1252C>G

1 paper

NM_002185.5

p.P417R

c.1250C>G

1 paper

NM_002185.5

p.P417A

c.1249C>G

1 paper

NM_002185.5

p.L421L

c.1263C>T

14 papers

NM_002185.5

p.T414M

c.1241C>T

1 paper

NM_002185.5

p.S423C

c.1268C>G

1 paper

NM_002185.5

p.S413N

c.1238G>A

7 papers

NM_002185.5

p.S413G

c.1237A>G

2 papers

NM_002185.5

p.N412I

c.1235A>T

3 papers

NM_002185.5

p.G424V

c.1271G>T

1 paper

NM_002185.5

p.G424_I425insFs

c.1272_1273ins4

1 paper

NM_002185.5

p.N412_L415del4

c.1234_1244del12