Varaico: Literature-Extracted Genetic Variants

IL7R

720 papers

RefSeq Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by ...

Pfam Domains

FN3_7aa 32–127UCSCFibronectin type III domain

fn3aa 130–224UCSCFibronectin type III domain

Gene Aliases

HGNC Name

interleukin 7 receptor

HGNC Alias Symbols

CD127; IL7RA; lnc-IL7R; IL-7Ralpha; IL7Ralpha; sIL-7R; CDw127

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002185.5

p.P430S

c.1288C>T

Surrounding Variants

1 paper

NM_002185.5

p.P430L

c.1289C>T

1 paper

NM_002185.5

p.A432D

c.1295C>A

1 paper

NM_002185.5

p.Q433H

c.1299G>C

1 paper

NM_002185.5

p.Q433H

c.1299G>T

1 paper

NM_002185.5

p.L426_T427insFs

c.1278_1279insG

1 paper

NM_002185.5

p.G434D

c.1301G>A

1 paper

NM_002185.5

p.I425T

c.1274T>C

1 paper

NM_002185.5

p.G424_I425insFs

c.1272_1273ins4

3 papers

NM_002185.5

p.G424V

c.1271G>T

1 paper

NM_002185.5

p.S423C

c.1268C>G

2 papers

NM_002185.5

p.I437_L438del2

c.1309_1313del6

1 paper

NM_002185.5

p.L421L

c.1263C>T