Varaico: Literature-Extracted Genetic Variants

IL7R

720 papers

RefSeq Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by ...

Pfam Domains

FN3_7aa 32–127UCSCFibronectin type III domain

fn3aa 130–224UCSCFibronectin type III domain

Gene Aliases

HGNC Name

interleukin 7 receptor

HGNC Alias Symbols

CD127; IL7RA; lnc-IL7R; IL-7Ralpha; IL7Ralpha; sIL-7R; CDw127

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002185.5

p.S443*

c.1328C>A

Surrounding Variants

1 paper

NM_002185.5

p.S443*

c.1328C>G

1 paper

NM_002185.5

p.N444Y

c.1330A>T

1 paper

NM_002185.5

p.Q445_E446insGG

c.1333_1337ins6

1 paper

NM_002185.5

p.L441R

c.1322T>G

1 paper

NM_002185.5

p.L441fs

c.1321_1322fs

1 paper

NM_002185.5

p.S440F

c.1319C>T

1 paper

NM_002185.5

p.S440delFs

c.1319delC

3 papers

NM_002185.5

p.T439S

c.1316C>G

4 papers

NM_002185.5

p.T439S

c.1315A>T

1 paper

NM_002185.5

p.Y449_V450insT

c.1345_1349ins3

4 papers

NM_002185.5

p.Y449F

c.1346A>T

2 papers

NM_002185.5

p.I437_L438del2

c.1309_1313del6