Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.G75C

INS

2,975 papers

RefSeq Summary

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translati...

Pfam Domains

Insulinaa 28–109UCSCInsulin/IGF/Relaxin family

Gene Aliases

HGNC Name

insulin

HGNC Previous Symbols

IDDM2; IDDM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000207.3
p.G75C
c.223G>T
Surrounding Variants
2 papers
NM_000207.3
p.G75_S76insK
c.223_227ins3
1 paper
NM_000207.3
p.G69_A74insFs
c.207_222dup16
1 paper
NM_000207.3
p.G75R
c.223G>C
3 papers
NM_000207.3
p.G75V
c.224G>T
1 paper
NM_000207.3
p.G75A
c.224G>C
2 papers
NM_000207.3
p.G75D
c.224G>A
1 paper
NM_000207.3
p.A74_G75delFs
c.222_223delCT
1 paper
NM_000207.3
p.A74delFs
c.221delG
1 paper
NM_000207.3
p.A74V
c.221C>T
1 paper
NM_000207.3
p.G75G
c.225C>G
2 papers
NM_000207.3
p.G75delFs
c.223delC
1 paper
NM_000207.3
p.G73_A74insFs
c.219_220insT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."