Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.G70R

INS

2,975 papers

RefSeq Summary

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translati...

Pfam Domains

Insulinaa 28–109UCSCInsulin/IGF/Relaxin family

Gene Aliases

HGNC Name

insulin

HGNC Previous Symbols

IDDM2; IDDM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000207.3
p.G70R
c.208G>C
Surrounding Variants
4 papers
NM_000207.3
p.G70R
c.208G>A
1 paper
NM_000207.3
p.G70V
c.209G>T
1 paper
NM_000207.3
p.G70A
c.209G>C
2 papers
NM_000207.3
p.G70E
c.209G>A
1 paper
NM_000207.3
p.G69G
c.207C>G
1 paper
NM_000207.3
p.G69_G70insFs
c.207_208insG
1 paper
NM_000207.3
p.G69delFs
c.206delC
1 paper
NM_000207.3
p.G70G
c.210G>T
1 paper
NM_000207.3
p.G70insFs
c.209_210insGA
1 paper
NM_000207.3
p.G70fs
c.208_209fs
1 paper
NM_000207.3
p.G69A
c.206G>C
3 papers
NM_000207.3
p.G69D
c.206G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."