Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.P52P

INS

2,975 papers

RefSeq Summary

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translati...

Pfam Domains

Insulinaa 28–109UCSCInsulin/IGF/Relaxin family

Gene Aliases

HGNC Name

insulin

HGNC Previous Symbols

IDDM2; IDDM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000207.3
p.P52P
c.156C>T
Surrounding Variants
1 paper
NM_000207.3
p.P52_K53insFs
c.156_157insGA
2 papers
NM_000207.3
p.P52P
c.156C>A
10 papers
NM_000207.3
p.P52L
c.155C>T
1 paper
NM_000207.3
p.P52R
c.155C>G
3 papers
NM_000207.3
p.P52H
c.155C>A
1 paper
NM_000207.3
p.Y50_T51delFs
c.150_151delTG
1 paper
NM_000207.3
p.K53*
c.157A>T
1 paper
NM_000207.3
p.K53_T54insC
c.157_161ins3
1 paper
NM_000207.3
p.K53_T54insAGA
c.157_161ins9
2 papers
NM_000207.3
p.P52S
c.154C>T
2 papers
NM_000207.3
p.P52T
c.154C>A
1 paper
NM_000207.3
p.K53R
c.158A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."