Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.P21P

INS

2,975 papers

RefSeq Summary

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translati...

Pfam Domains

Insulinaa 28–109UCSCInsulin/IGF/Relaxin family

Gene Aliases

HGNC Name

insulin

HGNC Previous Symbols

IDDM2; IDDM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000207.3
p.P21P
c.63A>G
Surrounding Variants
1 paper
NM_000207.3
p.P21P
c.63A>T
1 paper
NM_000207.3
p.P21_A22ins1
c.63_64insGGC
1 paper
NM_000207.3
p.P21_A22ins3
c.63_64ins9
2 papers
NM_000207.3
p.A22P
c.64G>C
1 paper
NM_000207.3
p.A22T
c.64G>A
1 paper
NM_000207.3
p.P21R
c.62C>G
1 paper
NM_000207.3
p.A22V
c.65C>T
1 paper
NM_000207.3
p.P21A
c.61C>G
1 paper
NM_000207.3
p.P21T
c.61C>A
2 papers
NM_000207.3
p.D20D
c.60C>T
1 paper
NM_000207.3
p.A22A
c.66C>T
4 papers
NM_000207.3
p.D20E
c.60C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."