Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.L11_A12insFs

INS

2,975 papers

RefSeq Summary

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translati...

Pfam Domains

Insulinaa 28–109UCSCInsulin/IGF/Relaxin family

Gene Aliases

HGNC Name

insulin

HGNC Previous Symbols

IDDM2; IDDM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000207.3
p.L11_A12insFs
c.33_34insT
Surrounding Variants
1 paper
NM_000207.3
p.L11fs
c.31_32fs
1 paper
NM_000207.3
p.L11L
c.33G>C
2 papers
NM_000207.3
p.L11insFs
c.31dupC
1 paper
NM_000207.3
p.L11P
c.32T>C
4 papers
NM_000207.3
p.A12S
c.34G>T
1 paper
NM_000207.3
p.A12insFs
c.34_35insCT
4 papers
NM_000207.3
p.A12P
c.34G>C
4 papers
NM_000207.3
p.A12T
c.34G>A
2 papers
NM_000207.3
p.A12V
c.35C>T
2 papers
NM_000207.3
p.L11L
c.31C>T
1 paper
NM_000207.3
p.A12G
c.35C>G
1 paper
NM_000207.3
p.L11V
c.31C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."