Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.A2Fs

INS

2,975 papers

RefSeq Summary

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translati...

Pfam Domains

Insulinaa 28–109UCSCInsulin/IGF/Relaxin family

Gene Aliases

HGNC Name

insulin

HGNC Previous Symbols

IDDM2; IDDM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000207.3
p.A2insFs
c.4_5insT
Surrounding Variants
2 papers
NM_000207.3
p.A2S
c.4G>T
1 paper
NM_000207.3
p.A2insFs
c.4_5insC
9 papers
NM_000207.3
p.A2T
c.4G>A
1 paper
NM_000207.3
p.A2fs
c.4_5fs
22 papers
NM_000207.3
p.M1I
c.3G>T
5 papers
NM_000207.3
p.M1insFs
c.2dupT
1 paper
NM_000207.3
p.M1delins
c.1delinsATTTTTA
13 papers
NM_000207.3
p.M1I
c.3G>C
26 papers
NM_000207.3
p.M1I
c.3G>A
1 paper
NM_000207.3
p.M1delFs
c.2delA
4 papers
NM_000207.3
p.A2V
c.5C>T
1 paper
NM_000207.3
p.A2G
c.5C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."