Varaico: Literature-Extracted Genetic Variants

INSC

39 papers

RefSeq Summary

In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically...

Pfam Domains

INSC_LBDaa 70–116UCSCInscuteable LGN-binding domain

Insc_Caa 127–579UCSCProtein inscuteable C-terminal

Gene Aliases

HGNC Name

INSC spindle orientation adaptor protein

HGNC Previous Name

inscuteable homolog (Drosophila)

Papers

RefSeq ID

Protein change

DNA change

1–12 of 47 variants

2 papers

NM_001042536.3

p.R115C

c.343C>T

2 papers

NM_001042536.3

p.V236I

c.706G>A

2 papers

NM_001042536.3

p.D282N

c.844G>A

1 paper

NM_001042536.3

p.L4M

c.10C>A

1 paper

NM_001031853.5

p.M70R

c.209T>G

1 paper

NM_001042536.3

p.V28_R30del0

c.83_88del6

1 paper

NM_001042536.3

p.E42K

c.124G>A

1 paper

NM_001042536.3

p.G66D

c.197G>A

1 paper

NM_001042536.3

p.V83_L88del6

c.247_263del18

1 paper

NM_001042536.3

p.S85_T86delFs

c.253_257del5

1 paper

NM_001042536.3

p.G92R

c.274G>A

1 paper

NM_001042536.3

p.G92R

c.274G>C