Varaico: Literature-Extracted Genetic Variants

INSC

39 papers

RefSeq Summary

In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically...

Pfam Domains

INSC_LBDaa 70–116UCSCInscuteable LGN-binding domain

Insc_Caa 127–579UCSCProtein inscuteable C-terminal

Gene Aliases

HGNC Name

INSC spindle orientation adaptor protein

HGNC Previous Name

inscuteable homolog (Drosophila)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001042536.3

p.T257delFs

c.770delC

Surrounding Variants

1 paper

NM_001042536.3

p.R256C

c.766C>T

1 paper

NM_001042536.3

p.Q253_T257del0

c.759_770del12

1 paper

NM_001042536.3

p.Q253_T257del5

c.757_770del15

1 paper

NM_001042536.3

p.R248_C262del15

c.742_785del45

1 paper

NM_001042536.3

p.F239delFs

c.715_716delTT

2 papers

NM_001042536.3

p.V236I

c.706G>A