Varaico: Literature-Extracted Genetic Variants

INSC

39 papers

RefSeq Summary

In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically...

Pfam Domains

INSC_LBDaa 70–116UCSCInscuteable LGN-binding domain

Insc_Caa 127–579UCSCProtein inscuteable C-terminal

Gene Aliases

HGNC Name

INSC spindle orientation adaptor protein

HGNC Previous Name

inscuteable homolog (Drosophila)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001042536.3

p.D282N

c.844G>A

Surrounding Variants

1 paper

NM_001042536.3

p.D282V

c.845A>T

1 paper

NM_001042536.3

p.C279F

c.836G>T

1 paper

NM_001042536.3

p.N287N

c.861C>T

1 paper

NM_001031853.5

p.G323V

c.968G>T

1 paper

NM_001042536.3

p.E296K

c.886G>A

1 paper

NM_001042536.3

p.E324V

c.971A>T

1 paper

NM_001042536.3

p.L329L

c.987C>T

1 paper

NM_001042536.3

p.L332Q

c.995T>A

1 paper

NM_001042536.3

p.S337*

c.1010C>A

1 paper

NM_001042536.3

p.S337*

c.1010C>G

1 paper

NM_001042536.3

p.L343P

c.1028T>C

1 paper

NM_001042536.3

p.A368D

c.1103C>A