Varaico: Literature-Extracted Genetic Variants

INTS6

85 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that intera...

Pfam Domains

VWA_2aa 4–133UCSCvon Willebrand factor type A domain

Beta-barrel_INTS6aa 252–398UCSCINTS6 beta-barrel domain

INT_SG_DDX_CT_Caa 807–869UCSCINTS6/SAGE1/DDX26B/CT45 C-terminus

Gene Aliases

HGNC Name

integrator complex subunit 6

HGNC Previous Symbol

DDX26

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_012141.3

p.T686A

c.2056A>G

Surrounding Variants

1 paper

NM_012141.3

p.L697P

c.2090T>C

1 paper

NM_012141.3

p.R658insFs

c.1973_1974insG

1 paper

NM_012141.3

p.R658Q

c.1973G>A

1 paper

NM_012141.3

p.E647Q

c.1939G>C

1 paper

NM_012141.3

p.R644*

c.1930C>T

3 papers

NM_012141.3

p.K643T

c.1928A>C

1 paper

NM_012141.3

p.Q639K

c.1915C>A

2 papers

NM_012141.3

p.E630A

c.1889A>C

1 paper

NM_012141.3

p.M626I

c.1878G>T

1 paper

NM_012141.3

p.M626I

c.1878G>C

1 paper

NM_012141.3

p.M626I

c.1878G>A

1 paper

NM_012141.3

p.G625S

c.1873G>A