Varaico: Literature-Extracted Genetic Variants

INTS6

85 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that intera...

Pfam Domains

VWA_2aa 4–133UCSCvon Willebrand factor type A domain

Beta-barrel_INTS6aa 252–398UCSCINTS6 beta-barrel domain

INT_SG_DDX_CT_Caa 807–869UCSCINTS6/SAGE1/DDX26B/CT45 C-terminus

Gene Aliases

HGNC Name

integrator complex subunit 6

HGNC Previous Symbol

DDX26

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012141.3

p.M382R

c.1145T>G

Surrounding Variants

1 paper

NM_012141.3

p.W348*

c.1044G>A

1 paper

NM_012141.3

p.W348*

c.1043G>A

1 paper

NM_012141.3

p.P344S

c.1030C>T

1 paper

NM_012141.3

p.S332L

c.995C>T

1 paper

NM_012141.3

p.K326*

c.976A>T

1 paper

NM_012141.3

p.P323fs

c.967_968fs

1 paper

NM_012141.3

p.H304Y

c.910C>T

1 paper

NM_012141.3

p.K398*

c.1192A>T

1 paper

NM_012141.3

p.H400R

c.1199A>G

2 papers

NM_012141.3

p.T405T

c.1215A>C

1 paper

NM_012141.3

p.W408*

c.1223G>A

1 paper

NM_012141.3

p.W408*

c.1224G>A