Varaico: Literature-Extracted Genetic Variants

INTS6

85 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that intera...

Pfam Domains

VWA_2aa 4–133UCSCvon Willebrand factor type A domain

Beta-barrel_INTS6aa 252–398UCSCINTS6 beta-barrel domain

INT_SG_DDX_CT_Caa 807–869UCSCINTS6/SAGE1/DDX26B/CT45 C-terminus

Gene Aliases

HGNC Name

integrator complex subunit 6

HGNC Previous Symbol

DDX26

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012141.3

p.E143K

c.427G>A

Surrounding Variants

2 papers

NM_012141.3

p.T137I

c.410C>T

1 paper

NM_012141.3

p.T137_S138insT

c.409_413ins3

1 paper

NM_012141.3

p.P122S

c.364C>T

1 paper

NM_012141.3

p.Q113_G114Splc

c.340-3T>C