Varaico: Literature-Extracted Genetic Variants

INTS7

49 papers

RefSeq Summary

This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and...

Pfam Domains

INTS7_Naa 26–538UCSCIntegrator complex subunit 7, N-terminal

INTS7_HBaa 539–720UCSCIntegrator complex subunit 7 helical bundle

INTS7_Caa 805–918UCSCIntegrator complex subunit 7, C-terminal domain

Gene Aliases

HGNC Name

integrator complex subunit 7

HGNC Previous Symbol

C1orf73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015434.4

p.R940C

c.2818C>T

Surrounding Variants

1 paper

NM_015434.4

p.D933N

c.2797G>A

1 paper

NM_015434.4

p.F962C

c.2885T>G

1 paper

NM_015434.4

p.N875H

c.2623A>C

1 paper

NM_015434.4

p.S856F

c.2567C>T

1 paper

NM_015434.4

p.R845C

c.2533C>T

1 paper

NM_015434.4

p.I782insFs

c.2345dupT