Varaico: Literature-Extracted Genetic Variants

INTS7

49 papers

RefSeq Summary

This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and...

Pfam Domains

INTS7_Naa 26–538UCSCIntegrator complex subunit 7, N-terminal

INTS7_HBaa 539–720UCSCIntegrator complex subunit 7 helical bundle

INTS7_Caa 805–918UCSCIntegrator complex subunit 7, C-terminal domain

Gene Aliases

HGNC Name

integrator complex subunit 7

HGNC Previous Symbol

C1orf73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015434.4

p.I370T

c.1109T>C

Surrounding Variants

1 paper

NM_015434.4

p.A386V

c.1157C>T

1 paper

NM_015434.4

p.S392S

c.1176C>T

2 papers

NM_015434.4

p.T408I

c.1223C>T

1 paper

NM_015434.4

p.A444T

c.1330G>A

1 paper

NM_015434.4

p.I447T

c.1340T>C

1 paper

NM_015434.4

p.L460M

c.1378C>A

1 paper

NM_015434.4

p.Q486*

c.1456C>T

1 paper

NM_015434.4

p.S329N

c.986G>A

1 paper

NM_015434.4

p.I322V

c.964A>G

1 paper

NM_015434.4

p.V496A

c.1487T>C

1 paper

NM_015434.4

p.N522S

c.1565A>G

1 paper

NM_015434.4

p.M536R

c.1607T>G