Varaico: Literature-Extracted Genetic Variants

Gene:IRAK1
Variant:p.A306T

IRAK1

294 papers

RefSeq Summary

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene...

Pfam Domains

Deathaa 27–103UCSCDeath domain
Pkinaseaa 212–517UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 1

HGNC Alias Symbol

pelle

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_001569.4
p.A306T
c.916G>A
Surrounding Variants
1 paper
NM_001569.4
p.Q305E
c.913C>G
1 paper
NM_001569.4
p.C307F
c.920G>T
1 paper
NM_001569.4
p.P309S
c.925C>T
1 paper
NM_001569.4
p.R315_L316insFs
c.945_946insC
1 paper
NM_001569.4
p.I318insFs
c.952_953insA
1 paper
NM_001569.4
p.I318N
c.953T>A
1 paper
NM_001569.4
p.I326V
c.976A>G
1 paper
NM_001569.4
p.I326insFs
c.977_978insC
1 paper
NM_001569.4
p.H330Y
c.988C>T
1 paper
NM_001569.4
p.P334S
c.1000C>T
1 paper
NM_001569.4
p.S335T
c.1004G>C
1 paper
NM_001569.4
p.H338insFs
c.1012_1013insT
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