Varaico: Literature-Extracted Genetic Variants

Gene:IRAK1
Variant:p.G219R

IRAK1

294 papers

RefSeq Summary

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene...

Pfam Domains

Deathaa 27–103UCSCDeath domain
Pkinaseaa 212–517UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 1

HGNC Alias Symbol

pelle

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001569.4
p.G219R
c.655G>A
Surrounding Variants
1 paper
NM_001569.4
p.G219R
c.655G>C
1 paper
NM_001569.4
p.I218F
c.652A>T
1 paper
NM_001569.4
p.G222G
c.666C>T
1 paper
NM_001569.4
p.S213A
c.637T>G
1 paper
NM_001569.4
p.V226M
c.676G>A
1 paper
NM_001569.4
p.T209T
c.627C>A
3 papers
NM_001569.4
p.T209A
c.625A>G
1 paper
NM_001569.4
p.G208G
c.624C>A
1 paper
NM_001569.4
p.R207delFs
c.620_621delCC
3 papers
NM_001569.4
p.C203W
c.609T>G
1 paper
NM_001569.4
p.T234M
c.701C>T
6 papers
NM_001569.4
p.C203S
c.608G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."