Varaico: Literature-Extracted Genetic Variants

Gene:IRAK1
Variant:p.L92L

IRAK1

294 papers

RefSeq Summary

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene...

Pfam Domains

Deathaa 27–103UCSCDeath domain
Pkinaseaa 212–517UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 1

HGNC Alias Symbol

pelle

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001569.4
p.L92L
c.276G>A
Surrounding Variants
3 papers
NM_001569.4
p.L93P
c.278T>C
1 paper
NM_001569.4
p.Q91Q
c.273G>A
1 paper
NM_001569.4
p.R94P
c.281G>C
1 paper
NM_001569.4
p.R96L
c.287G>T
1 paper
NM_001569.4
p.T88A
c.262A>G
1 paper
NM_001569.4
p.I99M
c.297C>G
1 paper
NM_001569.4
p.T100A
c.298A>G
1 paper
NM_001569.4
p.W102Splc
c.304+9G>A
4 papers
NM_001569.4
p.V80M
c.238G>A
1 paper
NM_001569.4
p.A78G
c.233C>G
1 paper
NM_001569.4
p.A78T
c.232G>A
3 papers
NM_001569.4
p.L70Q
c.209T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."