Varaico: Literature-Extracted Genetic Variants

Gene:IRAK1
Variant:p.F45_A46ins6

IRAK1

294 papers

RefSeq Summary

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene...

Pfam Domains

Deathaa 27–103UCSCDeath domain
Pkinaseaa 212–517UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 1

HGNC Alias Symbol

pelle

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_001569.4
p.F45_A46ins6
c.133_137ins18
Surrounding Variants
1 paper
NM_001569.4
p.A46S
c.136G>T
1 paper
NM_001569.4
p.C43R
c.127T>C
1 paper
NM_001569.4
p.A40insFs
c.118_119insA
1 paper
NM_001569.4
p.L37insFs
c.110_111insC
1 paper
NM_001569.4
p.M34L
c.100A>T
1 paper
NM_001569.4
p.V33insFs
c.98_99insA
2 papers
NM_001569.4
p.V33G
c.98T>G
1 paper
NM_001569.4
p.K32R
c.95A>G
1 paper
NM_001569.4
p.F30I
c.88T>A
1 paper
NM_001569.4
p.V22V
c.66G>C
1 paper
NM_001569.4
p.Y20*
c.60C>G
1 paper
NM_001569.4
p.Y20N
c.58T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."