Varaico: Literature-Extracted Genetic Variants

Gene:IRAK2
Variant:p.R147T

IRAK2

119 papers

RefSeq Summary

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is repo...

Pfam Domains

Deathaa 13–94UCSCDeath domain
Pkinaseaa 210–463UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_001570.4
p.R147T
c.440G>C
Surrounding Variants
1 paper
NM_001570.4
p.F153C
c.458T>G
1 paper
NM_001570.4
p.L154I
c.460C>A
1 paper
NM_001570.4
p.H163Y
c.487C>T
1 paper
NM_001570.4
p.S164S
c.492C>G
1 paper
NM_001570.4
p.R166R
c.498A>G
1 paper
NM_001570.4
p.S172L
c.515C>T
1 paper
NM_001570.4
p.G142Splc
c.425-1289G>A
1 paper
NM_001570.4
p.F197F
c.591C>T
1 paper
NM_001570.4
p.S199S
c.597T>C
4 papers
NM_001570.4
p.V203M
c.607G>A
1 paper
NM_001570.4
p.T207delFs
c.620_621delCC
5 papers
NM_001570.4
p.R214G
c.640C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."