Varaico: Literature-Extracted Genetic Variants

Gene:IRAK2
Variant:p.S199S

IRAK2

119 papers

RefSeq Summary

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is repo...

Pfam Domains

Deathaa 13–94UCSCDeath domain
Pkinaseaa 210–463UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001570.4
p.S199S
c.597T>C
Surrounding Variants
1 paper
NM_001570.4
p.F197F
c.591C>T
4 papers
NM_001570.4
p.V203M
c.607G>A
1 paper
NM_001570.4
p.T207delFs
c.620_621delCC
5 papers
NM_001570.4
p.R214G
c.640C>G
1 paper
NM_001570.4
p.R214H
c.641G>A
1 paper
NM_001570.4
p.Y225*
c.675C>A
1 paper
NM_001570.4
p.Y225*
c.675C>G
1 paper
NM_001570.4
p.H228L
c.683A>T
1 paper
NM_001570.4
p.V235I
c.703G>A
1 paper
NM_001570.4
p.R263Splc
c.789-125T>C
1 paper
NM_001570.4
p.S172L
c.515C>T
1 paper
NM_001570.4
p.R166R
c.498A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."