Varaico: Literature-Extracted Genetic Variants

Gene:IRAK2
Variant:p.D431E

IRAK2

119 papers

RefSeq Summary

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is repo...

Pfam Domains

Deathaa 13–94UCSCDeath domain
Pkinaseaa 210–463UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
12 papers
NM_001570.4
p.D431E
c.1293T>G
Surrounding Variants
12 papers
NM_001570.4
p.D431E
c.1293T>A
1 paper
NM_001570.4
p.S434C
c.1300A>T
1 paper
NM_001570.4
p.S438L
c.1313C>T
5 papers
NM_001570.4
p.L439V
c.1315C>G
4 papers
NM_001570.4
p.S441C
c.1322C>G
1 paper
NM_001570.4
p.V446M
c.1336G>A
1 paper
NM_001570.4
p.C455G
c.1363T>G
1 paper
NM_001570.4
p.E472A
c.1415A>C
1 paper
NM_001570.4
p.L424_K425Splc
c.1273-668T>C
1 paper
NM_001570.4
p.E491_V492Splc
c.1473+1523T>C
1 paper
NM_001570.4
p.E491_V492Splc
c.1474-1736C>T
1 paper
NM_001570.4
p.A498S
c.1492G>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."