Varaico: Literature-Extracted Genetic Variants

IRF2BP2

139 papers

RefSeq Summary

This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transc...

Pfam Domains

IRF-2BP1_2aa 12–63UCSCInterferon regulatory factor 2-binding protein zinc finger

IRF-2BP1_2_Maa 275–350UCSCIRF-2BP1/2 middle domain

zf-C3HC4_IRF-2BP1_2aa 504–575UCSCIRF-2BP1/2 C3HC4 zinc finger domain

Gene Aliases

HGNC Name

interferon regulatory factor 2 binding protein 2

HGNC Alias Symbols

LRIR2; IRF-2BP2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182972.3

p.P563L

c.1688C>T

Surrounding Variants

1 paper

NM_182972.3

p.V562D

c.1685T>A

1 paper

NM_182972.3

p.V562I

c.1684G>A

1 paper

NM_182972.3

p.A565del1

c.1693_1695delGGC

1 paper

NM_182972.3

p.G559insFs

c.1676dupG

1 paper

NM_182972.3

p.G559A

c.1676G>C

2 papers

NM_001077397.1

p.Q552*

c.1654C>T

NM_182972.3

p.Q568*

c.1702C>T

1 paper

NM_182972.3

p.I571fs

c.1711_1712fs

1 paper

NM_182972.3

p.C555S

c.1664G>C

1 paper

NM_182972.3

p.C555S

c.1663T>A

1 paper

NM_182972.3

p.E553fs

c.1657_1658fs

1 paper

NM_182972.3

p.G552R

c.1654G>A

1 paper

NM_182972.3

p.S551I

c.1652G>T