Varaico: Literature-Extracted Genetic Variants

IRF2BP2

139 papers

RefSeq Summary

This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transc...

Pfam Domains

IRF-2BP1_2aa 12–63UCSCInterferon regulatory factor 2-binding protein zinc finger

IRF-2BP1_2_Maa 275–350UCSCIRF-2BP1/2 middle domain

zf-C3HC4_IRF-2BP1_2aa 504–575UCSCIRF-2BP1/2 C3HC4 zinc finger domain

Gene Aliases

HGNC Name

interferon regulatory factor 2 binding protein 2

HGNC Alias Symbols

LRIR2; IRF-2BP2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182972.3

p.A444T

c.1330G>A

Surrounding Variants

1 paper

NM_182972.3

p.K442I

c.1325A>T

1 paper

NM_182972.3

p.Q446fs

c.1336_1337fs

1 paper

NM_182972.3

p.Q446*

c.1336C>T

1 paper

NM_182972.3

p.T450I

c.1349C>T

1 paper

NM_182972.3

p.G437G

c.1311C>T

1 paper

NM_182972.3

p.G436E

c.1307G>A

1 paper

NM_182972.3

p.S455N

c.1364G>A

1 paper

NM_182972.3

p.P458A

c.1372C>G

1 paper

NM_182972.3

p.P458R

c.1373C>G

1 paper

NM_182972.3

p.I429M

c.1287C>G

1 paper

NM_182972.3

p.P424S

c.1270C>T

1 paper

NM_182972.3

p.S462_M464ins1

c.1385_1390dup6