Varaico: Literature-Extracted Genetic Variants

IRF2BP2

139 papers

RefSeq Summary

This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transc...

Pfam Domains

IRF-2BP1_2aa 12–63UCSCInterferon regulatory factor 2-binding protein zinc finger

IRF-2BP1_2_Maa 275–350UCSCIRF-2BP1/2 middle domain

zf-C3HC4_IRF-2BP1_2aa 504–575UCSCIRF-2BP1/2 C3HC4 zinc finger domain

Gene Aliases

HGNC Name

interferon regulatory factor 2 binding protein 2

HGNC Alias Symbols

LRIR2; IRF-2BP2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182972.3

p.L188L

c.562C>T

Surrounding Variants

2 papers

NM_182972.3

p.P190S

c.568C>T

1 paper

NM_182972.3

p.M192V

c.574A>G

1 paper

NM_182972.3

p.N193Y

c.577A>T

1 paper

NM_182972.3

p.N193K

c.579C>G

1 paper

NM_182972.3

p.G194A

c.581G>C

3 papers

NM_182972.3

p.G194D

c.581G>A

1 paper

NM_182972.3

p.G194fs

c.580_581fs

2 papers

NM_182972.3

p.S195L

c.584C>T

1 paper

NM_182972.3

p.P198T

c.592C>A

1 paper

NM_182972.3

p.G194_T197delFs

c.581_591del11

2 papers

NM_182972.3

p.L199L

c.597G>A

1 paper

NM_182972.3

p.P200L

c.599C>T