Varaico: Literature-Extracted Genetic Variants

Gene:IRF3
Variant:p.I220M

IRF3

393 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms...

Pfam Domains

IRFaa 7–110UCSCInterferon regulatory factor transcription factor
IRF-3aa 55–234UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001571.6
p.I220M
c.660C>G
Surrounding Variants
1 paper
NM_001571.6
p.S221A
c.661T>G
1 paper
NM_001571.6
p.I220F
c.658A>T
1 paper
NM_001571.6
p.P223S
c.667C>T
1 paper
NM_001571.6
p.E224A
c.671A>C
1 paper
NM_001571.6
p.G225fs
c.673_674fs
1 paper
NM_001571.6
p.R227R
c.681G>A
1 paper
NM_001571.6
p.R213delFs
c.638delC
2 papers
NM_001571.6
p.R211Q
c.632G>A
4 papers
NM_001571.6
p.G230A
c.689G>C
1 paper
NM_001571.6
p.G230fs
c.688_689fs
1 paper
NM_001571.6
p.F209F
c.627C>T
1 paper
NM_001571.6
p.A208D
c.623C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."