Varaico: Literature-Extracted Genetic Variants

Gene:IRF4
Variant:p.E45*

IRF4

406 papers

RefSeq Summary

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are...

Pfam Domains

IRFaa 23–128UCSCInterferon regulatory factor transcription factor
IRF-3aa 249–418UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 4

HGNC Previous Symbol

MUM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_002460.4
p.E45*
c.133G>T
Surrounding Variants
1 paper
NM_002460.4
p.E45K
c.133G>A
1 paper
NM_002460.4
p.N44K
c.132C>A
1 paper
NM_002460.4
p.N44K
c.132C>G
1 paper
NM_002460.4
p.E46del1
c.136_137delGAG
2 papers
NM_002460.4
p.N44S
c.131A>G
1 paper
NM_002460.4
p.E46_F50del0
c.136_150del15
1 paper
NM_002460.4
p.E46K
c.136G>A
1 paper
NM_002460.4
p.E46Q
c.136G>C
1 paper
NM_002460.4
p.E43D
c.129G>C
1 paper
NM_002460.4
p.E43D
c.129G>T
1 paper
NM_002460.4
p.E43G
c.128A>G
1 paper
NM_002460.4
p.E46D
c.138G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."