Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006147.4

p.S424*

c.1271C>A

Surrounding Variants

8 papers

NM_006147.4

p.S424L

c.1271C>T

4 papers

NM_006147.4

p.S424*

c.1271C>G

4 papers

NM_006147.4

p.S424A

c.1270T>G

1 paper

NM_006147.4

p.L421_I423del3

c.1261_1268del9

1 paper

NM_006147.4

p.I423S

c.1268T>G

5 papers

NM_006147.4

p.I423T

c.1268T>C

1 paper

NM_006147.4

p.P426S

c.1276C>T

5 papers

NM_006147.4

p.Q422*

c.1264C>T

2 papers

NM_006147.4

p.P426delFs

c.1277delG

4 papers

NM_006147.4

p.D427Y

c.1279G>T

2 papers

NM_006147.4

p.L421R

c.1262T>G

1 paper

NM_006147.4

p.D427G

c.1280A>G