Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

18 papers

NM_006147.4

p.R400W

c.1198C>T

Surrounding Variants

1 paper

NM_006147.4

p.A399fs

c.1195_1196fs

2 papers

NM_006147.4

p.R400P

c.1199G>C

12 papers

NM_006147.4

p.R400Q

c.1199G>A

1 paper

NM_006147.4

p.A399delFs

c.1195delC

5 papers

NM_006147.4

p.V397A

c.1190T>C

3 papers

NM_006147.4

p.V397E

c.1190T>A

5 papers

NM_006147.4

p.Y403*

c.1209C>G

4 papers

NM_006147.4

p.Y403*

c.1209C>A

7 papers

NM_006147.4

p.E404K

c.1210G>A

11 papers

NM_006147.4

p.P396S

c.1186C>T

1 paper

NM_006147.4

p.E404G

c.1211A>G

4 papers

NM_006147.4

p.M405T

c.1214T>C