Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006147.4

p.L345P

c.1034T>C

Surrounding Variants

1 paper

NM_006147.4

p.F346L

c.1036T>C

1 paper

NM_006147.4

p.F346L

c.1038T>G

1 paper

NM_006147.4

p.F346L

c.1038T>A

6 papers

NM_006147.4

p.C347F

c.1040G>T

1 paper

NM_006147.4

p.E349*

c.1045G>T

4 papers

NM_006147.4

p.E349V

c.1046A>T

2 papers

NM_006147.4

p.I337_Q340delFs

c.1011_1020del10

1 paper

NM_006147.4

p.T350K

c.1049C>A

2 papers

NM_006147.4

p.F351L

c.1051T>C

1 paper

NM_006147.4

p.F351S

c.1052T>C

4 papers

NM_006147.4

p.R339I

c.1016G>T

2 papers

NM_006147.4

p.F351L

c.1053C>G